Gerresheimer has unveiled a new metal-free 1ml long Luer Lock Gx RTF syringe, which serves as primary packaging solution for sophisticated medications.
The syringe has been developed to be used for medications based on biotechnologically manufactured active ingredients, in a bid to avoid contamination with metal.
Luer Lock Gx RTF syringe, which is available in various sizes, will be showcased at the 20th Pharmapack event in France.
The pin used to shape the cone has been made with special ceramic, making it free from tungsten or an alternative metal.
According to Gerresheimer, the Institut Fresenius neither found ceramic particles nor detected tissue reactions in a separate bio-compatibility study.
Generally, pre-fillable syringes will be used for the storage and administering of biotechnological medications.
These syringes will undergo siliconization to hydrophobize glass surface, providing complete emptying capability for the medication. It will also help in a low level of interaction of the active ingredient with the glass.
According to the firm, the high silicone quantities may result in the formation of the smallest silicone droplets in the solution onto which the active ingredient can coagulate and is then no longer bioavailable.
The firm’s baked-on RTF syringes, which are patented in Europe and the US, features a technology that achieves gap-free coating with the lowest quantities of silicone.
In addition, the syringes can be equipped with thin-walled cannulas to enhance administering of highly viscous medications.
Gerresheimer produces pharmaceutical packaging products, as well as drug delivery systems such as insulin pens, inhalers, pre-fillable syringes, vials, ampoules.
The firm also produces bottles and containers for liquid and solid pharmaceuticals with closure and safety systems, in addition to cosmetic packaging products.
