Canada-based pharmaceutical company Apotex, on behalf of the manufacturer Hospira, has issued a voluntary recall of 15 lots of Piperacillin and Tazobactam for Injection, USP 40.5 grams, in the US.
The affected lots of Piperacillin and Tazobactam for Injection, USP 40.5 grams may show precipitation / crystallization in IV bag or IV line after reconstitution, which results in local reactions such as phlebitis, renal impairment, end-organ embolism and ischemia, and/or vasculitis.
The precipitation of the drug may also not allow delivering a needed therapeutic dose of piperacillin and tazobactam to target infection.
The affected Piperacillin and Tazobactam for Injection, USP 40.5 grams lots include the product stating NDC number 60505-0773-00 and UPC 360505077304, which were packaged in 300 mL glass vials for reconstitution and distributed nationwide.
