The US FDA has approved Janssen Biotech's Simponi ARIA (golimumab) for infusion to treat moderately to severely active rheumatoid arthritis (RA). Simponi ARIA is the only fully-human anti-tumor necrosis factor (TNF)-alpha infusible ...
Clinical stage biopharma company Rexahn Pharmaceuticals has entered into an exclusive licensing agreement with the University of Maryland, Baltimore (UMB), for a novel drug delivery platform, which targets the delivery of chemotherapeutic ...
Tags: Rexahn Pharma, Oncology Drug
The Italian Medicines Agency (AIFA) has granted market access to Cell Therapeutics for the medicinal product, Pixuvri (pixantrone), a novel aza-anthracenedione with structural and physiochemical properties Pixuvri has been approved as a ...
The US Patent and Trademark Office (USPTO) has issued a notice of patent allowance for DelMar Pharmaceuticals’ first-in-class small-molecule chemotherapeutic VAL-083. The patent covers the methods for synthesizing VAL-083, which is ...
AOP Orphan Pharmaceuticals has announced the spin-off of its 80% stake in Activartis, a Vienna-based biotech company, to a group of private investors. Activartis has developed dendritic cell-based technology for individualized tumor ...
Tags: AOP Orphan, Medicine
The US Food and Drug Administration (FDA) has given its clearance to Amgen's XGEVA (denosumab) to treat adult or skeletally mature patients suffering from giant cell tumor of bone (GCTB). Approved after conducting a priority review, XGEVA ...
Tags: Amgen's XGEVA, Medicine
Stemline Therapeutics' SL-401 has won orphan drug designation from the Food and Drug Administration (FDA) for the treatment of aggressive hematologic malignancy blastic plasmacytoid dendritic cell neoplasm (BPDCN). With an orphan drug ...
Tags: Stemline Therapeutic, Orphan Drug
The US Patent and Trademark Office (USPTO) has granted a patent to GenSpera for the activation of peptide prodrugs by HK2, which is an enzyme secreted by prostate cancer cells. Composition of a series of prodrugs activated by HK2 enzyme ...
Tags: Peptide Prodrugs, Medicine
Inostics, a molecular diagnostics firm providing blood-based mutation testing, has received the Clinical Laboratory Improvement Amendments (CLIA) license for its clinical laboratory in Baltimore. The receipt of the license would mark a ...
Tags: Clia Certification, Medicine
US-based company Arno has entered into partnership with Veridex, a Johnson & Johnson company, to develop a diagnostic test that detects the presence of activated progesterone receptors (APRs) as a biomarker of anti-progestin activity in ...
Tags: Arno, Diagnostic Test
Alethia Biotherapeutics has gained US patent for methods of treating carcinomas with antibodies targeting the region of secreted clusterin (sCLU) responsible for promoting epithelial-to-mesenchymal transition (EMT). The company along with ...
Tags: Alethia, US Patent, Cancer Treatment Methods
ImmunoCellular Therapeutics has obtained US patent for methods of use of interleukin 13-receptor alpha 2 protein (IL-13Rα2) in cancer immunotherapy. IL-13 is an immune regulatory cytokine and IL-13Ra2 is highly and specifically ...
Tags: Immunocellular, US Patent, Alpha 2 Protein
Sterling Insurance has expanded its Critical Condition plan offering in 18 additional US states, marking the availability of the new type of insurance to 31 states. The plan comprises 11 critical illnesses, which includes cancer, stroke, ...
Tags: Sterling Insurance, Insurance
Janssen Biotech has announced the FDA approval of Simponi (golimumab) to treat moderately to severely active ulcerative colitis (UC) in adult patients with corticosteroid dependence or an inadequate response to or failed to tolerate oral ...
Tags: FDA, Janssen Biotech
Prometheus Laboratories is enrolling patients for Proclivity 01, a multi-center study of Proleukin (High Dose Interleukin-2 (HD IL-2)) combined with vemurafenib therapy in patients with Braf V600 mutation-positive metastatic melanoma (mM). ...
Tags: Prometheus, Proclivity 01 Study