MakieLab also picks up an Entertainment and Gaming award.
Over 100,000 digital Makie doll characters have been created to date.
The news comes as creator of the 3D printed dolls, MakieLab, is honoured at the SXSW 5th Annual Accelerator competition in Austin, Texas.
The London-based firm took the top prize in the Entertainment and Gaming Technologies category.
Following a live pitch by MakieLab’s CEO Alice Taylor, the start-up joined the winners’ circle from what judges agreed was "an extremely strong field" in this year’s competition, which highlights companies with fresh ideas, strong creative visions and exceptional business potential.
Over 500 total submissions were received for the 2013 SXSW Accelerator, culminating in awards for seven of the web’s most exciting new innovations across web, mobile, social, entertainment/gaming, news, health and music categories.
“We are delighted, humbled and grateful to the wonderful people of SXSW for this award,” said Taylor.
"We've had the most amazing five days here, and this finale is the icing on the cake. It seems to be the year of 3D printing: Bre Pettis keynoting, Bruce Sterling wearing a 3D-printed Bruce Sterling around his neck... it’s fantastic, and we're very much enjoying being part of this movement."
In February, Makies became the world’s first 3D-printed toy to earn the CE mark, certifying them as safe for kids aged three and above.
Makies Doll Factory, MakieLab’s free build-a-doll app for iPad, was released earlier this month.