The National Institutes of Health (NIH) has awarded a Phase I small business innovation research (SBIR) grant to TriLink BioTechnologies to use its expertise in nucleic acid chemistry and develop an approach to RNA sample preparation for Next Generation Sequencing (NGS).
Under $130,000 grant, TriLink plans to investigate methods to reduce formation of adapter dimers during RNA sample preparation, which will remove the need for gel purification prior to sequencing.
TriLink BioTechnologies CEO Richard Hogrefe said the company is pleased to utilize its strengths in the modification of nucleic acids to support the evolution of the technology.
"Improving the process of RNA sample preparation for next generation sequencing will increase the accessibility of this valuable tool," Hogrefe added.
SBIR grant principal investigator Natasha Paul said, "We are pleased to contribute to this growing field streamline NGS sample preparation workflows for small RNA deep sequencing."
