Babies who develop leukemia during the first year of life appear to inherit an unfortunate combination of genetic variations that can make the infants highly susceptible to the disease, according to a new study at Washington University ...
Tags: Leukemia, Genetic Predisposition, DNA, gene
To develop correctly, baby hearts need rhythm...even before they have blood to pump. "We have discovered that mechanical forces are important when making baby hearts," said Mary Kathryn Sewell-Loftin, a Vanderbilt graduate student working ...
Tags: Baby Heart, Rhythm, Roadmap, SysCODE
Work uncovers secret of how genome-editing tool works as a 'guided missile' to correct errors in the genetic code Researchers from the Broad Institute and MIT have teamed up with colleagues from the University of Tokyo to form the first ...
A group of researchers at the Institute for Research in Immunology and Cancer (IRIC) of Universit- de Montr-al discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That ...
Tags: Immunology and Cancer(IRIC), Leukemia Treatment, Brg1 gene
The discovery of seven new regions of DNA linked to type 2 diabetes could lead to new ways of thinking about diabetes and new treatments for the disease, researchers suggest. The findings were among the results of the largest study to ...
Tags: genetic effects, compiled genetic information, biology of the disease
Findings suggest drugs can now be developed to stall the growth of K-Ras cancers, previously deemed impossible to treat NYU Langone Medical Center researchers have found a biological weakness in the workings of the most commonly mutated ...
Tags: K-Ras, DNA, radiation, Mutated Gene
Patients with a common form of lung cancer — lung squamous cell carcinoma — have very few treatment options. That situation may soon change. A team of cancer biologists at Mayo Clinic in Florida is reporting in the Feb. 10 ...
Tags: Oncogene, lung cancer, PKCiota, SOX2
Inspired by tiny particles that carry cholesterol through the body, MIT chemical engineers have designed nanoparticles that can deliver snippets of genetic material that turn off disease-causing genes. This approach, known as RNA ...
Tags: RNA, MIT, Gene Silencing, Nanoparticle
New research is lighting up yet another reason for women to quit smoking. In a study published online in the journal Menopause, researchers from the Perelman School of Medicine at the University of Pennsylvania report the first evidence ...
Tags: White Woman, Genetic Variation, Menopause, Smoking
In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a potentially general approach to design drugs from genome sequence. As a proof of ...
Tags: Identify New Drug Candidates, unparalleled selectivity, cell permeable
What is antibiotic resistance and is it correct to describe it as a ‘looming global threat’? Antibiotic resistance is a consequence of antibiotic use. Bacteria adapt to the threat of antibiotics using mechanisms to overcome ...
Tags: Addressing Antibiotic Resistance, bacteria, implementing policies
The first large-scale study testing all the DNA—the entire genome—of tumour cells from more than 400 women with advanced breast cancer has identified individuals with a good chance of benefiting from specific treatments already ...
Tags: CGH, SAFIR01, DNA, Gustave Roussy
Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice. Their findings, they report, may help ...
Abnormal number of chromosomes is often associated with cancer development. In a new study published in the journal Nature Structural and Molecular Biology researchers at Karolinska Institutet in Sweden have shown that a subtle epigenetic ...
Scientists have pieced together sections of DNA from 12 individual cells to sequence the genome of a bacterium known to live in healthy human mouths. With this new data about a part of the body considered "biological dark matter," the ...